Credit: Jian Yang, Yixue Su Artist’s conception of nanoparticle-carrying immune cells that target tumors and release drug-loaded nanoparticles for cancer treatment.
Penn State engineers have conjugating biodegradable polymer nanoparticles encapsulated with chosen cancer-fighting drugs into immune cells to create a smart, targeted system to attack cancers of specific types. “The traditional way to deliver drugs to tumors is to put the drug inside some type of nanoparticle and inject those particles into the bloodstream,” said Jian Yang, professor of biomedical engineering, Penn State. “Because the particles are so small, if they happen to reach the tumor site they have a chance of penetrating through the blood vessel wall because the vasculature of tumors is usually leaky.”
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