bioelectronics tagged posts

Complementary logic circuit Photo credit: Thor Balkhed

Complementary logic circuits based on high-performance n-type organic electrochemical transistor. Researchers at the Laboratory of Organic Electronics, Linköping University, have developed the world’s first complementary electrochemical logic circuits that can function stably for long periods in water. This is a highly significant breakthrough in the development of bioelectronics.

The first printable organic electrochemical transistors were presented by researchers at LiU as early as 2002, and research since then has progressed rapidly. Several organic electronic components, such as light-emitting diodes and electrochromic displays, are already commercially available.

The dominating material used until now has been PEDOT:PSS, which is...

This image illustrates changes in photocurrent before and after exposure to UV light. Persistent photoconductivity is demonstrated even hours after the UV light has been turned off. This is illustrated by the pictograms showing charge carriers that come into contact with cells at the interface during in vitro experiments. Credit: Albena Ivanisevic

Researchers have developed a new approach for manipulating the behavior of cells on semiconductor materials, using light to alter the conductivity of the material itself. Albena Ivanisevic, a professor of materials science and engineering at NC Stat said: “Our work here effectively adds another tool to the toolbox for the development of new bioelectronic devices.” The new approach uses a phenomenon called persistent photoconductivity...

DanielSimon and Theresia Arbring Sjöström. Credit: Image courtesy of Linköping Universitet

With a microfabricated ion pump built from organic electronic components, ions can be sent to nerve or muscle cells at the speed of the nervous system and with a precision of a single cell. “Now we can start to develop components that speak the body’s own language,” says Daniel Simon, Laboratory of Organic Electronics, Linköping University. Certain substances, such as GABA, are important signal substances throughout the CNS. 18 months ago, researchers at the Laboratory of Organic Electronics demonstrated an ion pump which researchers at the Karolinska Institutet could use to reduce the sensation of pain in awake, freely-moving rats. The ion pump delivered GABA directly to the rat´s spinal cord.

Intestinal organs (stock image). There’s evidence that manufacturing biologically inspired “smart pills” can be cost-effective and pass regulatory approval. Credit: © nerthuz / Fotolia

Imagine a “smart pill” that can sense problems in your intestines and actively release the appropriate drugs. We have the biological understanding to create such a device, but we’re still searching for electronic materials (like batteries and circuits) that pose no risk if they get stuck in our bodies. Christopher Bettinger of Carnegie Mellon University presents a vision for creating safe, consumable electronics, such as those powered by the charged ions within our digestive tracts.

Edible electronic medical devices are not a new idea...