biomarker tagged posts

Scale of how chronic fatigue syndrome affects patients’ blood shown for first time

Scale of how myalgic encephalomyelitis/chronic fatigue syndrome affects patients' blood shown for first time
Study design and overview of results. Credit: EMBO Molecular Medicine (2025). DOI: 10.1038/s44321-025-00258-8

People with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) have significant differences in their blood compared with healthy individuals, a new study reveals, suggesting a path toward more reliable diagnosis of the long-term debilitating illness. The paper is published in the journal EMBO Molecular Medicine.

The largest ever biological study of ME/CFS has identified consistent blood differences associated with chronic inflammation, insulin resistance, and liver disease.

Significantly, the results were mostly unaffected by patients’ activity levels, as low activity levels can sometimes hide the biological signs of illness, experts say.

The volume and cons...

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Finger Wrap uses Sweat to provide Health Monitoring at your Fingertips

This finger wrap is powered by the wearer’s fingertip sweat—and also monitors levels of glucose, lactate, vitamin C and levodopa in that same sweat. Credit: Shichao Ding

A sweat-powered wearable has the potential to make continuous, personalized health monitoring as effortless as wearing a Band-Aid. Engineers at the University of California San Diego have developed an electronic finger wrap that monitors vital chemical levels—such as glucose, vitamins, and even drugs—present in the same fingertip sweat from which it derives its energy.

The advance was published Sept. 3 in Nature Electronics by the research group of Joseph Wang, a professor in the Aiiso Yufeng Li Family Department of Chemical and Nano Engineering at UC San Diego.

The device, which wraps snugly around the fin...

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No more Needles for Diagnostic Tests?

Engineers at the McKelvey School of Engineering at Washington University in St. Louis have developed a microneedle patch that can be applied to the skin, capture a biomarker of interest from interstitial fluid and, thanks to its unprecedented sensitivity, allow clinicians to detect its presence.(Image: Sisi Cao)

Nearly pain-free microneedle patch can test for antibodies and more in the fluid between cells. Medical researchers have developed a biosensing microneedle patch that can be applied to the skin, capture a biomarker of interest and, thanks to its unprecedented sensitivity, allow clinicians to detect its presence.

Blood draws are no fun. They hurt. Veins can burst, or even roll — like they’re trying to avoid the needle, too...

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Green Tea cuts Obesity, Health Risks in Mice

Green tea.
Credit: © KMNPhoto / Fotolia

Follow-up study in people underway. Green tea cut obesity and a number of inflammatory biomarkers linked with poor health in a new study. Mice fed a diet of 2% green tea extract fared far better than those that ate a diet without it, a finding that has prompted an upcoming study of green tea’s potential benefits in people at high risk of diabetes and heart disease.

The benefits seen in the new study, published in the Journal of Nutritional Biochemistry, appear to stem from improved gut health, including more beneficial microbes in the intestines of the mice and less permeability in the intestinal wall – a condition typically called “leaky gut” in people.

“This study provides evidence that green tea encourages the growth of good gut bacter...

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