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A common biomarker of schizophrenia and bipolar disorder revealed

A common biomarker of schizophrenia and bipolar disorder
Altered brain connectivity across diagnoses. The meta-analysis revealed consistent alterations in white matter connectivity across psychosis-spectrum disorders, including schizophrenia and bipolar disorder. Credit: Merola et al.

For decades, schizophrenia and bipolar disorder (BD) were treated as distinct and unrelated psychiatric disorders. Schizophrenia is a psychiatric disorder characterized by altered thinking and emotional patterns, hallucinations, false or irrational beliefs (i.e., delusions), cognitive deficits, and disorganized speech. BD, on the other hand, is marked by extreme mood swings, ranging between periods of high-energy (i.e., mania or hypomania) and depressive episodes.

While the symptoms of schizophrenia and BD are markedly different, many patients diagnosed with...

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