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    Biomarkers tagged posts

    New Alzheimer’s Disease Pathways identified

    October 9, 2023, Categories  Biology/Biotechnology, Health/Medical

    New Alzheimer's disease pathways identified
    Path model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed variables. Arrows either indicate PC loadings or structural regression paths. Thicker lines correspond to stronger loadings, solid structural paths are genome-wide significant (p < 5 × 10−8), and dashed lines are suggestive (p < 0.008). Coefficients indicate either the effect of one effect allele on a biomarker PC in SD, or the effect of one SD higher biomarker PC score on latent AD in SD. Note: all paths are adjusted for assessment age, sex, genetic ancestry, and study but are omitted from figure. Credit: Genome Medicine (2023). DOI: 10.1186/s13073-023-01233-z

    Dementia, which includes Alzheimer’...

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    Simple Blood Test may Predict Future Heart, Kidney Risk for people with Type 2 Diabetes

    August 22, 2023, Categories  Biology/Biotechnology, Health/Medical

    blood draw - man
    blood draw – man
    copyright American Heart Association

    An analysis of a clinical trial of more than 2,500 people with Type 2 diabetes and kidney disease found that high levels of four biomarkers are strongly predictive for the development of heart and kidney issues.

    A simple blood test may predict the risk of progressive heart and kidney disease in people with Type 2 diabetes and kidney disease, according to new research published today in the American Heart Association’s flagship journal Circulation.

    “High levels of certain biomarkers are indicators of heart and kidney complications and may help predict future risk of disease progression,” said lead author James Januzzi, M.D...

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    Researchers find a New Class of Biomarkers to Predict Treatment Outcomes in Cancer Patients

    June 26, 2023, Categories  Biology/Biotechnology, Health/Medical

    Researchers find a new of biomarkers to predict treatment outcomes in cancer patients
    Cancer is the result of the uncontrolled division and spread of cells into surrounding tissue. Recently researchers have begun to focus on biomarkers as a source of information about different cancers, how they work in the body, and how they can be fought. Credit: Colin Behrens/Pixabay, CC0 Public Domain

    One of the big reasons that cancer is difficult to treat is that patients respond to treatments differently, and these differences can rarely be anticipated. In most cases, determining whether and how a patient will respond to any given therapy requires administering it to the patient and then waiting and watching. That is a lot of pressure for researchers and physicians and a lot of risk for cancer patients, and added expense.

    If a patient’s response were predictable, optimal thera...

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    New DNA Biosensor could unlock Powerful, Low-Cost Clinical Diagnostics

    January 26, 2023, Categories  Biology/Biotechnology, Health/Medical

    A graphical representation of a DNA biosensor device for clinical diagnostics that is the size and shape of a smartphone.
    In a new study, researchers demonstrate the capability of DNA biosensor components for a unique modular DNA biosensor. The researchers plan to integrate their design within a device the size and shape of a smartphone for low-cost clinical diagnostics. 
    Credit: N. Hanacek/NIST

    DNA can signal the presence of or predisposition to a slew of diseases, including cancer. The ability to flag down these clues, known as biomarkers, allows medical professionals to make critical early diagnoses and provide personalized treatments. The typical methods of screening can be laborious, expensive or limited in what they can uncover. A new biosensor chip that boasts an accurate and inexpensive design may increase accessibility to high-quality diagnostics.

    The biosensor, developed by researchers at the ...

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