biomaterials tagged posts

Bacteria ‘Nanowires’ could help Develop Green Electronics

Bacteria 'nanowires' could help develop green electronics
Structure of γPFD filaments and incorporation of heme to make conductive nanowires. a) Filament assembly of γPFD through β-sheet domains, and b) proposed binding of heme molecules to the coiled-coil domains to form γPFD-heme nanowires. c) Protein-ligand binding isotherm with 30 µm of γPFD and varying concentration of heme, which indicates a stochiometric ratio of ≈1 heme per γPFD subunit in filaments. d) TEM image of the γPFD-heme nanowires. Credit: Small (2024). DOI: 10.1002/smll.202311661

Engineered protein filaments originally produced by bacteria have been modified by scientists to conduct electricity...

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First-ever Spider Glue Genes Sequenced, paving way to next Biomaterials breakthrough

Aggregate spider glue from three spider types. (A) Orb weavers coat their web’s sticky capture spiral with glue, (B) cobweb weavers cover the lower portion of their triplines with glue to create ’gumfoot’ threads, (C) the bolas spider creates a large droplet of glue specialized for capturing moths, and (D) A stretching glue droplet after contacting a probe that was subsequently withdrawn at a constant rate. Inset images courtesy of Brent Opell.

Huge spider glue genes proved exceptionally challenging to sequence, could lead to organic pest control and more. Researchers have determined the first-ever complete sequences of two spider glue genes...

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3D Bioprinting technique could create Artificial Blood Vessels, Organ Tissue

Orthogonal programming of matrix stiffness and geometry via oxygen inhibition-assisted stereolithography.

Orthogonal programming of matrix stiffness and geometry via oxygen inhibition-assisted stereolithography.

University of Colorado Boulder engineers have developed a 3D printing technique that allows for localized control of an object’s firmness, opening up new biomedical avenues that could one day include artificial arteries and organ tissue. The study, which was recently published in the journal Nature Communications, outlines a layer-by-layer printing method that features fine-grain, programmable control over rigidity, allowing researchers to mimic the complex geometry of blood vessels that are highly structured and yet must remain pliable.

The findings could one day lead to better, more personalized treatments for those suffering from hypertension and other vascular diseases...

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Stingray Soft Robot could lead to Bio-Inspired Robotics

Artist’s concept of a stingray soft robot. (Image: UCLA)

Artist’s concept of a stingray soft robot. (Image: UCLA)

UCLA bioengineering professor Ali Khademhosseini has led the development of a tissue-based soft robot that mimics the biomechanics of a stingray. The new technology could lead to advances in bio-inspired robotics, regenerative medicine and medical diagnostics. The simple body design of stingrays, specifically, a flattened body shape and side fins that start at the head and end at the base of their tail, makes them ideal to model bio-electromechanical systems on.

The 10-millimeter long robot is made up of four layers: tissue composed of live heart cells, two distinct types of specialized biomaterials for structural support, and flexible electrodes...

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