Opioid use is highly effective for pain management but is associated with high rates of addiction and deaths due to overdose. Now, an international team of researchers has developed a soft, bioresorbable, implantable device which can provide a cooling effect to peripheral nerves, leading to blocking of pain signals. The device demonstrated high precision and efficacy in rat models with spared nerve injuries and can serve as an effective substitute for opioids.
Owing to their high efficacy, opioids are used widely for the management of neuropathic pain, despite the increasing rates of opioid addiction and deaths due to overdose. To avoid these side effects, there is an urgent need for pain management approaches that can substitute opioid use.
It is well known that cold temperatur...
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