Potential mechanisms contributing to low bone mass and increased fracture susceptibility in diabetes mellitus.
“Clinical trials have revealed a startling elevation in fracture risk in diabetic patients,” says Liyun Wang, associate professor of mechanical engineering at the University of Delaware. “Bone fractures can be life threatening – nearly one in six hip fracture patients dies within a year of injury.” As physical exercise is proven to improve bone properties and reduce fracture risk in non-diabetic people, Wang’s group decided to test its efficacy in Type 1 diabetes.
Osteocytes are critical to maintenance of the tissue quality and mechanical integrity of bone...
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