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Missing Immune Cells that could Fight Lethal Brain Tumors

Researchers at Duke Cancer Institute have tracked the missing T-cells in glioblastoma patients in the bone marrow, locked away and unable to function because of a process the brain stimulates in response to glioblastoma, to other tumors that metastasize in the brain and even to injury. Credit: Alisa Weigandt for Duke Health

Researchers at Duke Cancer Institute have tracked the missing T-cells in glioblastoma patients in the bone marrow, locked away and unable to function because of a process the brain stimulates in response to glioblastoma, to other tumors that metastasize in the brain and even to injury.
Credit: Alisa Weigandt for Duke Health

A mysterious lack of T-cells has hindered the immune system’s ability to fight glioblastoma. Researchers have tracked the missing T-cells in glioblastoma patients. They found them in abundance in the bone marrow, locked away and unable to function because of a process the brain stimulates in response to glioblastoma, to other tumors that metastasize in the brain and even to injury.

Glioblastoma brain tumors can have an unusual effect on the body’s immune system, often ca...

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