bone strength tagged posts

Researchers uncover a key protein and a promising strategy to prevent bone damage from steroids

The rheumatology and orthopedic researchers discovered that a protein called Basigin, which gets activated in stem cells when people take steroids, is a key reason why bones weaken and blood vessels in bone tissue become abnormal. By blocking Basigin, they were able to protect and even restore bone health in mice, suggesting a promising new treatment path.

Their findings were published in Nature Communications.

“This research is a major step forward in understanding how steroid treatments affect bone health,” said Thomas H. Ambrosi, assistant professor in the Department of Orthopedic Surgery and co-corresponding author of the study...

Soy protein improves tibial whole-bone and tissue-level biomechanical properties in ovariectomized and ovary-intact, low-fit female rats. Bone Reports, 2018; 8: 244 DOI: 10.1016/j.bonr.2018.05.002

Researchers now have discovered through a new animal study that soy protein found in food might counter the negative effects of menopause on bone and metabolic health. Moreover, the researchers believe that soy protein might also have positive impacts on bone strength for women who have not yet reached menopause.

Osteoporosis, decreased physical activity and weight gain are serious health concerns for postmenopausal women...