Schematic of mice with dysfunctional and functional Wnt signaling Source: Alzheimer’s Research UK
Memory loss in mice has been reversed following the discovery of new information about a key mechanism underlying the loss of nerve connectivity in the brain. The team found Wnt proteins play a key role in the maintenance of nerve connectivity in the adult brain and could become targets for new treatments that prevent and restore brain function in neurodegenerative diseases.
Professor Salinas said: “Synapses are absolutely critical to everything that our brains do. When these important communication points are lost, nerve cells cannot exchange information and this leads to symptoms like memory and thinking problems...
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