Do more with one link - claim and personalize your FREE link today! Effortlessly schedule, video meet, message chat, network, share materials, e-sign, etc – all in one spot. Collaborate, Nurture connections, Improve client services, Expedite deal closures, and more. 💼 Join FREE!!

Recent Comments

    brain stem cells tagged posts

    How a Longevity Gene protects Brain Stem Cells from Stress

    February 23, 2021, Categories  Biology/Biotechnology, Health/Medical

    cells under a microscope
    Antioxidant treatment boosts the birth of new neurons from stem cells by suppressing stress signaling. Image courtesy of the Paik lab.

    A gene linked to unusually long lifespans in humans protects brain stem cells from the harmful effects of stress, according to a new study by Weill Cornell Medicine investigators.

    Studies of humans who live longer than 100 years have shown that many share an unusual version of a gene called Forkhead box protein O3 (FOXO3). That discovery led Dr. Jihye Paik, associate professor of pathology and laboratory medicine at Weill Cornell Medicine, and her colleagues to investigate how this gene contributes to brain health during aging.

    In 2018, Dr...

    Read More

    Zika Virus may cause Microcephaly by Hijacking Human Immune Molecule

    May 6, 2016, Categories  Biology/Biotechnology, Health/Medical

    In a 3-D brain model, Zika virus activates immune receptor TLR3, which in turn inhibits brain cell development and survival, causing the organoids to shrink -- an effect reminiscent of microcephaly. Credit: UC San Diego Health

    In a 3-D brain model, Zika virus activates immune receptor TLR3, which in turn inhibits brain cell development and survival, causing the organoids to shrink — an effect reminiscent of microcephaly. Credit: UC San Diego Health

    Fetal brain model provides first clues on how Zika virus blunts brain development; blocking mechanism reduces cell damage, hinting at a new therapeutic approach to mitigate effects of prenatal Zika virus infection. Using a 3D, stem cell-based model of a first-trimester human brain, the team discovered that Zika activates TLR3, a molecule human cells normally use to defend against invading viruses. In turn, hyper-activated TLR3 turns off genes that stem cells need to specialize into brain cells and turns on genes that trigger cell suicide...

    Read More

    Forever Young? A Barrier against Brain Stem Cell Aging

    September 18, 2015, Categories  Biology/Biotechnology, Health/Medical

    The stem cells asymmetrically segregate damaged proteins (red) between the mother and the daughter cells (on the left: DNA grey). Responsible for this is a diffusion barrier. The strength of the barrier weakens with advancing age. This leads to reduced asymmetry of damaged protein segregation (on the right). Credit: UZH

    The stem cells asymmetrically segregate damaged proteins (red) between the mother and the daughter cells (on the left: DNA grey). Responsible for this is a diffusion barrier. The strength of the barrier weakens with advancing age. This leads to reduced asymmetry of damaged protein segregation (on the right). Credit: UZH

    Neural stem cells generate new neurons throughout life in the mammalian brain. However, with advancing age the potential for regeneration in the brain dramatically declines. Scientists of the University of Zurich now identified a novel mechanism of how neural stem cells stay relatively free of aging-induced damage. A diffusion barrier regulates the sorting of damaged proteins during cell division.

    Barriere

    Dividing neural stem cells (outlined with a white line) establish a diffusion...

    Read More