brain tumor tagged posts

Boosting the Immune System’s Appetite for Cancer

Brain Tumor
UTSW
Brain Tumor

Immunotherapy combo that encourages immune cells to consume tumors could lead to long-term remission for glioblastoma. A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission, a new study led by UT Southwestern scientists suggests. The finding, published online March 20, 2020, in Nature Communications, could lead to new therapies that may significantly extend survival for human glioblastoma patients, which stands at an average of 15 months after diagnosis even with current state-of-the-art therapies.

The immune system has two branches: innate immunity, an evolutionarily older system that continually scans the b...

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Laser-based SRS Imaging Tool could Increase Accuracy, Safety of Brain Tumor Surgery

Images collected using an SRS microscope show that normal brain contains sparse cells with bundles of nerve fibers, called axons (left), but brain tumor tissue is full of cells in a disordered pattern (right). While you can see the difference on a microscopic scale, during surgery they’d be difficult to differentiate, making it hard for a surgeon to know where the tumor stops. Credit: Image courtesy of University of Michigan Health System

Images collected using an SRS microscope show that normal brain contains sparse cells with bundles of nerve fibers, called axons (left), but brain tumor tissue is full of cells in a disordered pattern (right). While you can see the difference on a microscopic scale, during surgery they’d be difficult to differentiate, making it hard for a surgeon to know where the tumor stops. Credit: Image courtesy of University of Michigan Health System

New tech gives brain surgeons real-time microscopic vision of tumors, potentially allowing the surgical decision-making process to become data driven, instead of subjective “best guesses,”. Even the state-of-the-art imaging equipment in today’s OR still doesn’t make the process much easier...

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