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    Composition of Joint Lubricant potential Culprit behind Osteoarthritis

    April 18, 2023, Categories  Biology/Biotechnology, Health/Medical

    The complex interplay between phospholipid and hyaluronic acid self-assembly in solution, and the molecular weight of hyaluronic acid, determine surface affinity and the formation of a protective film on cartilage. Credit: Kangdi Sun, Tooba Shoaib, Mark W. Rutland, Changwoo Do, and Rosa M. Espinosa-Marzal

    Neutron and light scattering, along with atomic force microscopy and quartz crystal microbalance, illuminate a mechanism explaining the ‘vicious circle’ of osteoarthritis.

    The exact mechanism of cartilage breakdown in osteoarthritis is unknown, but damage from mechanical stress with insufficient self-repair is believed to be the main culprit...

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