Mild cold and exercise stimulate creation of “beige fat” in white adipose tissue
It triggers a surprising metabolic mechanism: white fat cells are transformed into cells similar to brown fat ( ‘beige fat’), that protects the body against excess weight and its damaging consequences. In healthy humans, white adipose tissue constitutes ~25% of body mass. However, when in excess, white fat contributes to insulin resistance and diabetes. Conversely, brown fat improves insulin sensitivity and is reversely correlated to obesity.
In response to cold or exercise, cells similar to brown fat – the beige fat – can appear within the white fat, a phenomenon known as “browning...
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