The dentate gyrus of the mouse hippocampal formation which contributes to the formation of new episodic memories stained for neurons (green) and stem cells (red). Credit: Andrew L Bashford and Vasanta Subramanian University of Bath
Scientists identify 2 regions of mouse brains where C9orf72 is expressed. For the first time novel expression sites in the brain have been identified for a gene which is associated with Motor Neuron Disease and Frontotemporal Dementia. Many people who develop Motor Neuron Disease, also called Amyotropic Lateral Sclerosis (ALS), and/or Frontotemporal Dementia (FTD) have abnormal repeats of nucleotides within a gene called C9orf72 which causes neurons to die.
A team from the Department of Biology & Biochemistry at the University of Bath discovered for the first ti...
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