cancer biomarker tagged posts

This new blood test could detect cancer before it shows up on scans

Caption: When the biomarker is detected, the Cas12a protein used for CRISPR cuts the DNA holding the quantum dots, which causes a measurable drop in SHG signal.
Credit: Han Zhang, Shenzhen University

A new CRISPR-powered light sensor can detect the faintest molecular signs of cancer in a drop of blood. A new light-based sensor can spot incredibly tiny amounts of cancer biomarkers in blood, raising the possibility of earlier and simpler cancer detection. The technology merges DNAnanotechnology, CRISPR, and quantumdots to generate a clear signal from just a few molecules. In lung cancer tests, it worked even in real patient serum samples. Researchers hope it could eventually power portable blood tests for cancer and other diseases.

Scientists have designed a powerful light based sensor...

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Ultrafast Detection of a Cancer Biomarker enabled by innovative Nanobiodevice

(A) An image of the nanobiodevice (left), an SEM image of the hybrid structure of nanopillars and nanoslits (middle), and the magnified SEM image (right). (B) Schematic of the hybrid structure of nanopillars and nanoslits around the cross injector. (C) Diagram showing the scheme of sample injection. Figure panels C-a to C-e are arranged by time in ascending order. Sample of nucleic acids and direction of electrophoretic migration are depicted in green diagonal and blue arrows, respectively. Suggested dominant mechanisms for each process are shown at the bottom.

(A) An image of the nanobiodevice (left), an SEM image of the hybrid structure of nanopillars and nanoslits (middle), and the magnified SEM image (right). (B) Schematic of the hybrid structure of nanopillars and nanoslits around the cross injector. (C) Diagram showing the scheme of sample injection. Figure panels C-a to C-e are arranged by time in ascending order. Sample of nucleic acids and direction of electrophoretic migration are depicted in green diagonal and blue arrows, respectively. Suggested dominant mechanisms for each process are shown at the bottom.

A nanobiodevice that can quickly and effectively separate microRNA from mixtures of nucleic acids has been developed...

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Portable Smartphone Laboratory Detects Cancer at Once

Washington State University researchers have developed a low-cost, portable laboratory on a smartphone that can analyze several samples at once to catch a cancer biomarker, producing lab quality results. Credit: Washington State University

Washington State University researchers have developed a low-cost, portable laboratory on a smartphone that can analyze several samples at once to catch a cancer biomarker, producing lab quality results. Credit: Washington State University

Researchers have developed a low-cost, portable laboratory on a smartphone that can analyze several samples at once to catch a cancer biomarker, producing lab quality results. At a time when patients and medical professionals expect always faster results, researchers are trying to translate biodetection technologies used in laboratories to the field and clinic, so patients can get nearly instant diagnoses in a physician’s office, ambulance or emergency room.

The WSU research team created an 8 channel smartphone spectrometer that can detect human interleu...

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