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Researchers Kill Drug-Resistant Lung Cancer with 50 times Less Chemo

Drug-resistant lung cancer cells are in red. Paclitaxel-loaded exosomes (green) swarm the cancer cells and bypass their drug resistance. Credit: UNC Eshelman School of Pharmacy

Drug-resistant lung cancer cells are in red. Paclitaxel-loaded exosomes (green) swarm the cancer cells and bypass their drug resistance. Credit: UNC Eshelman School of Pharmacy

The cancer drug paclitaxel just got more effective. For the first time, researchers from the University of North Carolina at Chapel Hill have packaged it in containers derived from a patient’s own immune system, protecting the drug from being destroyed by the body’s own defenses and bringing the entire payload to the tumor. “That means we can use 50 times less of the drug and still get the same results,” said A/Prof Elena Batrakova, Ph.D...

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