cancer treatment tagged posts

Controlling Spatial Heat and Light Distribution by Using Photothermal Enhancing Auto-Regulated Liposomes (PEARLs).

Dr. Gang Zheng and a team of biomedical researchers have discovered a “smart” organic, biodegradable nanoparticle that uses heat and light in a controlled manner to potentially target and ablate tumours with greater precision. The proof-of-concept findings provide a viable approach to boosting the clinical utility of photo-thermal therapy in treating cancer, says Dr. Zheng, Senior Scientist at the Princess Margaret and Professor of Medical Biophysics at the University of Toronto.He talks about and demonstrates the research at https://youtu.be/EEN6Mz5iWBI.

In the lab, using phantom models, the “smart” nanoparticle the team has dubbed PEARLs – photo-thermal enhancing auto-regula...

ProAgio induces apoptosis by recruiting caspase 8, that plays an essential role in programmed cell death, to the cytoplasmic area of integrin v3

A protein designed Georgia State Uni researchers can effectively target a cell surface receptor linked to a number of diseases, showing potential as a therapeutic treatment for an array of illnesses, including cancer. ProAgio, which is created from a human protein, targets the cell surface receptor integrin v3 at a novel site that has not been targeted by other scientists. The researchers found ProAgio induces apoptosis of cells that express integrin v3. This integrin has been a focus for drug development because abnormal expression of v3 is linked to the development and progression of a number of diseases.

“This integrin pair, v3, is not expresse...