CAPON tagged posts

Alzheimer’s disease Protein links Plaques to Cell Death in mice

MRI scans of CAPON-overexpressing mouse brains scanned 7 days and 3 months after CAPON cDNA introduction to AD mice.
CREDIT: RIKEN

A new protein involved in Alzheimer’s disease (AD) has been identified by researchers at the RIKEN Center for Brain Science (CBS). CAPON may facilitate the connection between the two most well-known AD culprits, amyloid plaques and tau pathology, whose interactions cause brain cell death and symptoms of dementia. This latest finding from the Takaomi Saido group at RIKEN CBS uses a novel mouse model of AD. The study was published in Nature Communications on June 3.

Alzheimer’s disease is a complex and devastating condition characterized by plaques of amyloid-β and neurofibrillary tangles, also known as tau pathology, in the brain...

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