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    CAR T cell therapies tagged posts

    Research demonstrates that Killer T cells can support Tissue Regeneration

    January 17, 2024, Categories  Biology/Biotechnology, Health/Medical

    Killer T cells support tissue regeneration
    Wound healing and target killing are both effector mechanisms of CD8 T cells. (A) Combined proliferation and killing assay in the presence of influenza-specific CD8 T cells and varying amounts of pulsed peptides on MRC-5 and HaCaT cells seeded in a 30:70 ratio. Left, representative image with labels (0 versus 5 h; T cells only versus T cells + 100 ng/ml peptide). Right, representative quantification of Cas3/7 activity (green) and HaCaT proliferation (red) with titrated amounts of influenza peptide, with statistical verification across experiments using normalized area under the curve (AUC, n = 3, one-way ANOVA, symbols indicate individual experiments). Scale bars = 400 µm; enhanced for improved visibility...
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