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Lab Creates new class of Hydrogen Sulfide Donor molecules

University of Oregon lab creates new class of hydrogen sulfide donor molecules

Illustration shows the delivery route of hydrogen sulfide to damaged cells based on two projects completed in the University of Oregon lab of Michael Pluth. Credit: Michael Pluth

Molecules with the potential to deliver healing power to stressed cells – such as those involved in heart attacks – have been created by University of Oregon researchers. The research – done at a cellular level in the lab and far from medical reality – involves the design of organic molecules that break down to release hydrogen sulfide when triggered by specific conditions such as increased oxidative stress. Oxidative stress damages cells and is tied especially to heart disease and cancer, as well as Alzheimer’s and Parkinson’s disease.

“We have discovered that small organic molecules can be engineered to release ...

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