cardiovascular disease tagged posts

Multiple Urinary Metals play Key Role in Cardiovascular disease and Mortality, study finds

Higher levels of urinary metals such as cadmium, tungsten, uranium, cobalt, copper and zinc are linked to increased cardiovascular disease and mortality in a racially and ethnically diverse U.S. population, according to a new study at Columbia University Mailman School of Public Health. While it is well documented that exposure to certain metals has been associated with cardiovascular disease (CVD) and mortality, until now the evidence was limited beyond arsenic, cadmium, and lead and for a racially diverse population. The findings are published in the journal Circulation.

When analyzed together, the 6 metal-mixture including cadmium, tungsten, uranium, copper, cobalt, and zinc was associated with a 29 percent increased risk of cardiovascular disease and a 66% increased risk of dea...

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Study finds Common Artificial Sweetener linked to Higher Rates of Heart Attack and Stroke

New Cleveland Clinic research showed that erythritol, a popular artificial sweetener, is associated with an increased risk of heart attack and stroke. Findings were published today in Nature Medicine.

Researchers studied more than 4,000 people in the U.S. and Europe and found those with higher blood erythritol levels were at elevated risk of experiencing a major adverse cardiac event such as heart attack, stroke or death. They also examined the effects of adding erythritol to either whole blood or isolated platelets. Results revealed that erythritol made platelets easier to activate and form a clot. Pre-clinical studies confirmed ingestion of erythritol heightened clot formation.

“Sweeteners like erythritol, have rapidly increased in popularity in recent years but there needs to...

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The ‘Guardian of the Genome’ Protects against Cardiovascular Disease

The 'guardian of the genome' protects against cardiovascular disease
The analysis of human samples and animal experiments demonstrate that the presence of p53 gene mutations in the blood increases the risk of developing atherosclerosis, the principle cause of cardiovascular disease. Credit: CNIC

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), working in collaboration with institutes in the U.S., has demonstrated that acquired mutations in the gene encoding the protein p53 contribute to the development of atherosclerotic cardiovascular disease.

Known as the “guardian of the genome,” p53 helps to maintain the integrity of the hereditary material inside cells by regulating multiple cell functions in response to cellular stresses.

Every day, an adult person generates hundreds of thousands of blood cells...

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30-60 mins of Weekly Muscle Strengthening Activity linked to 10-20% Lower Death Risk

Credit: Unsplash/CC0 Public Domain

Between 30 and 60 minutes of muscle strengthening activity every week is linked to a 10-20% lower risk of death from all causes, and from cardiovascular disease, diabetes, and cancer, in particular, finds a pooled data analysis of the available evidence, published online in the British Journal of Sports Medicine.

The findings are independent of aerobic exercise. But the analysis points to a J-shaped curve for most outcomes, with no conclusive evidence that more than an hour a week of muscle strengthening activity reduces the risk further still.

Physical activity guidelines recommend regular muscle strengthening activities for adults, primarily because of the known benefits for skeletal muscle health...

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