Protective effects of mitochondria-targeted antioxidants and statins on cholesterol-induced osteoarthritis
High cholesterol might harm more than our cardiovascular systems. New research using animal models, published online in The FASEB Journal, suggests that high cholesterol levels trigger mitochondrial oxidative stress on cartilage cells, causing them to die, and ultimately leading to the development of osteoarthritis. This research tested the potential therapeutic role of mitochondria targeting antioxidants in high-cholesterol-induced osteoarthritis and provided proof-of-concept for the use of mitochondrial targeting antioxidants to treat osteoarthritis.
“Our team has already begun working alongside dietitians to try to educate the public about healthy eating and how to keep cholesterol...
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