Cervical Cancer tagged posts

Urine Test could prevent Cervical Cancer, study finds

A comparison of the mean ct values for detection of the internal beta globin control and HR-HPV in urine, vaginal and cervical samples using the ART (A,B) and RC assays (C,D). ct, cycle threshold; HPV, human papillomavirus. 

Urine testing may be as effective as the smear test at preventing cervical cancer, according to new research by University of Manchester scientists. The study, led by Dr Emma Crosbie and published in BMJ Open, found that urine testing was just as good as the cervical smear at picking up high-risk human papillomavirus (HPV), the virus that causes cervical cancer.

The research team say a urine test could help increase the numbers of women who are screened for cervical cancer, which affects more than 3,000 women every year in the UK.
Urine testing could also have...

Read More

Scientists Advance a Novel Urine Test to Predict High-Risk Cervical Cancer

Cervical cancer Signs & Symptoms, Prevention & Rx

Johns Hopkins Medicine specialists report they have developed a urine test for the likely emergence of cervical cancer that is highly accurate compared to other tests based on genetic markers derived directly from cervical tissue. The new urine test, they say, is different because it analyzes not only multiple sources of human cellular DNA altered by precancerous changes, but also DNA from HPV that is sexually transmitted and causes virtually all cases of the disease.

In a proof-of-concept study the investigators say their genetic markers test showed a “sensitivity” or accuracy rate of 90...

Read More

Genetically Engineered DNA Vaccine Eradicates High-Grade Precancerous Cervical Lesions in nearly 1/2 of women in clinical trial

DNA Vaccine

The goal was to find nonsurgical ways to treat precancerous lesions caused by HPV. “Every standard therapeutic option for women with these lesions destroys part of the cervix, which is particularly relevant for women of childbearing age, who may then be at risk for preterm birth due to a weakened cervix,” says Prof. Cornelia Trimble, M.D. “A vaccine able to cure precancerous lesions could eventually be one way women can avoid surgery that is invasive and can also harm their fertility.”

High-grade cervical lesions, termed CIN2/3, occur most often in women 40 or younger. Because the lesions can progress to cancer, they are usually removed by surgery, freezing or laser. The procedures are successful in removing the precancerous areas in approximately 80% of women...

Read More