Newly identified toxin common in E. coli bacteria accelerated colon cancer in study mice; confirming link to human colorectal cancers could pave way for developing preventive drugs. The discovery raises the possibility that some of the roughly two million new cases of colorectal cancer every year around the world originate from brief and seemingly mild food-poisoning events. It also points to the possibility of future drugs that prevent colorectal cancers by neutralizing the newly identified toxin, UshA.
The findings were published January 12 in the January edition of Cancer Discovery.
Prior research has suggested that certain bacteria that reside in the gut can trigger colorectal cancer via persistent infections involving chronic gut inflammation...
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