Chronic pain tagged posts

Gut Bacteria associated with Chronic Pain for first time

Human gut microbiome composition shows an enormous richness. Each circle represents a bacterial species, while the different colours mark different bacterial phyla. Credit: Dr. Amir Minerbi

People with fibromyalgia show variations in microbiome composition. A research team has shown, for the first time, that there are alterations in the bacteria in the gastrointestinal tracts of people with fibromyalgia. Approximately 20 different species of bacteria were found in either greater or are lesser quantities in the microbiomes of participants suffering from the disease than in the healthy control group.

Fibromyalgia affects 2-4 percent of the population and has no known cure...

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Does Insulin Resistance cause Fibromyalgia?


Effect of metformin treatment on pain as measured by the NPRS (0–10 scale).

A newly confirmed link with insulin resistance may radically change the way fibromyalgia and related forms of chronic pain are identified and managed. Researchers led by a team from The University of Texas Medical Branch at Galveston were able to dramatically reduce the pain of fibromyalgia patients with medication that targeted insulin resistance.

This discovery could dramatically alter the way that chronic pain can be identified and managed. Dr. Miguel Pappolla, UTMB professor of neurology, said that although the discovery is very preliminary, it may lead to a revolutionary shift on how fibromyalgia and related forms of chronic pain are treated...

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Laughter may be Best Medicine – for Brain Surgery

Illustration showing how an electrode was inserted into the cingulum bundle.
Credit: From Bijanki et al, J. Clin. Invest. (2019); Courtesy of American Society for Clinical Investigation

Effects of electrical stimulation of cingulum bundle. Neuroscientists at Emory University School of Medicine have discovered a focal pathway in the brain that when electrically stimulated causes immediate laughter, followed by a sense of calm and happiness, even during awake brain surgery. The effects of stimulation were observed in an epilepsy patient undergoing diagnostic monitoring for seizure diagnosis. These effects were then harnessed to help her complete a separate awake brain surgery two days later.

The behavioral effects of direct electrical stimulation of the cingulum bundle, a white matte...

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Promise in Light Therapy to Treat Chronic Pain

Rats were exposed to room light and fitted with contact lenses, one shown here, that allowed the green spectrum wavelength to pass through the lenses. (Photo: Bob Demers/UANews)

Rats were exposed to room light and fitted with contact lenses, one shown here, that allowed the green spectrum wavelength to pass through the lenses. (Photo: Bob Demers/UANews)

Chronic pain afflicts over 100 million people across the US. But now researchers at the University of Arizona have found promise in a novel, non-pharmacological approach to managing chronic pain – treating it with green light-emitting diodes (LED). In the study, rats with neuropathic pain that were bathed in green LED showed more tolerance for thermal and tactile stimulus than rats that were not bathed in green LED. In both cases no side effects from the therapy were observed, nor was motor or visual performance impaired. The beneficial effects lasted for 4 days after the rats’ last exposure to the green LED...

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