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    chronic stress tagged posts

    Brain Regions that Relieve Effects of Chronic Stress in Mice Differ based on Sex

    December 18, 2024, Categories  Biology/Biotechnology, Health/Medical

    Schematic of cortical microcircuit showing connections among neurons and how activation of SST neurons leads to stress resilience
    New research finds sex-specific regions of the brain can relieve the detrimental effects of chronic stress in male and female mice. Left: Schematic showing a cortical microcircuit with three types of interneurons expressing somatostatin (SST), parvalbumin (PV) or vasointestinal peptide (VIP) and their distinct patterns of innervation of glutamatergic output neurons (PNs), with thin lines representing axons that send chemical signals and the thicker lines of PNs representing dendrites that receive information. There is selective innervation of the distal ends of PN dendrites by axons of SST neurons...
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    Chronic Stress Accelerates Colorectal Cancer Progression by Disrupting the Balance of Gut Microbiota, study shows

    October 15, 2024, Categories  Biology/Biotechnology, Health/Medical

    intestine
    Credit: CC0 Public Domain

    Cutting-edge research has uncovered how chronic stress disrupts the balance of gut microbiota to speed up the progression of colorectal cancer (CRC), opening new avenues for CRC prevention and treatment.

    By eliminating certain gut bacteria and inducing stress, researchers were able to conclude a relationship between stress and gut microbiota in the progression of CRC, identifying a particular bacterial species as a potential therapeutic target.

    Presenting the study at UEG Week 2024, lead researcher Dr...

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    Regenerating Hair Follicle Stem Cells

    April 2, 2021, Categories  Biology/Biotechnology, Health/Medical

    Mouse hair follicle.
    Underneath the mouse hair follicle, dermal papilla cells (green) produce the Gas6 molecule that activates hair follicle stem cells. Credit: Hsu Laboratory, Harvard University

    Harvard University researchers have identified the biological mechanism of how chronic stress impairs hair follicle stem cells, confirming long-standing observations that stress might lead to hair loss.

    In a mouse study published in the journal Nature, the researchers found that a major stress hormone causes hair follicle stem cells to stay in an extended resting phase, without regenerating the hair follicle and hair...

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