These are neurons (c-fos, green) in the rat central amygdala activated by E. coli proteins in stationary phase and surrounded by nerve terminals (calcitonin gene-related peptide, red) originating from anorexigenic brainstem projections. Credit: J. Breton, N. Lucas & D. Schapman.
Don’t have room for dessert? The bacteria in your gut may be telling you something. 20 min after a meal, gut microbes produce proteins that can suppress food intake in animals, reports a study. The researchers also show how these proteins injected into mice and rats act on the brain reducing appetite, suggesting that gut bacteria may help control when and how much we eat.
The new evidence coexists with current models of appetite control, which involve hormones from the gut signalling to brain circuits when we’re hu...
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