colon tagged posts

This image is a mouse intestinal organoid, or “mini-gut,” used to study epithelial cell barrier function in ongoing inflammatory bowel disease and cancer studies. Photo courtesy of Coy Allen. Credit: Virginia Tech

Could inflammatory bowel disease and colon cancer be prevented by changing the shape of a single protein? There is an intimate link between uncontrolled inflammation in the gut associated with inflammatory bowel disease and the eventual development of colon cancer. This uncontrolled inflammation is associated with changes in bacteria populations in the gut, which can invade the mucosal tissue after damage to the protective cellular barrier lining the tissue.
But Virginia Tech researchers found that modifying the shape of IRAK-M, a protein that controls inflammation, can significa...

Lifetime report of perceived stress at work and cancer among men: A case-control study in Montreal, Canada. Preventive Medicine, 2017; 96: 28 DOI: 10.1016/j.ypmed.2016.12.004

1st study on the link between cancer and work-related stress perceived by men throughout their working lifetime. For men, prolonged exposure to work-related stress has been linked to an increased likelihood of lung, colon, rectal, and stomach cancer and non-Hodgkin lymphoma. The findings are among the results obtained by researchers at INRS and Université de Montréal who conducted the first study to assess the link between cancer and work-related stress perceived by men throughout their working life. The results were recently published in Preventive Medicine.

On average, the study participants had held 4 jobs, with ...