colorectal cancer tagged posts

Probiotic Delivers Anti-cancer Drug to the Gut

illustration of yeast Saccharomyces cerevisiae
Researchers at WashU Medicine shrink gastrointestinal tumors in mice using a yeast probiotic to deliver immunotherapy to the gut, offering a potentially novel strategy to target hard-to-reach gut cancers.

Oral immunotherapy shrinks gastrointestinal tumors in mouse study

Immunotherapy is a promising treatment that recruits the immune system to help fight cancer, but it has had limited success in gastrointestinal cancers. Now, researchers at Washington University School of Medicine in St. Louis have engineered a probiotic that delivers immunotherapy directly to the gut to shrink tumors in mice, offering a potentially promising oral drug for hard-to-reach cancers.

The probiotic cancer treatment, described Nov...

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Chronic Stress Accelerates Colorectal Cancer Progression by Disrupting the Balance of Gut Microbiota, study shows

intestine
Credit: CC0 Public Domain

Cutting-edge research has uncovered how chronic stress disrupts the balance of gut microbiota to speed up the progression of colorectal cancer (CRC), opening new avenues for CRC prevention and treatment.

By eliminating certain gut bacteria and inducing stress, researchers were able to conclude a relationship between stress and gut microbiota in the progression of CRC, identifying a particular bacterial species as a potential therapeutic target.

Presenting the study at UEG Week 2024, lead researcher Dr...

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‘Drug factory’ Implants Eliminate Ovarian, Colorectal Cancer in Mice

Rice University bioengineers Amanda Nash (left) and Omid Veiseh with vials of bead-like “drug factories” they created to treat cancer. The beads are designed to continuously produce natural compounds that program the immune system to attack tumors. (Photo by Jeff Fitlow/Rice University)

Immunotherapy treatment could begin human clinical trials this year. Rice University bioengineers have shown they can eradicate advanced-stage ovarian and colorectal cancer in mice in as little as six days with a treatment that could be ready for human clinical trials later this year.

The researchers used implantable “drug factories” the size of a pinhead to deliver continuous, high doses of interleukin2, a natural compound that activates white blood cells to fight cancer...

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Artificial Intelligence to Detect Colorectal Cancer

A Tulane University researcher found that artificial intelligence can accurately detect and diagnose colorectal cancer from tissue scans as well or better than pathologists, according to a new study in the journal Nature Communications.

The study, which was conducted by researchers from Tulane, Central South University in China, the University of Oklahoma Health Sciences Center, Temple University, and Florida State University, was designed to test whether AI could be a tool to help pathologists keep pace with the rising demand for their services.

Pathologists evaluate and label thousands of histopathology images on a regular basis to tell whether someone has cancer...

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