colorectal cancer tagged posts

‘Drug factory’ Implants Eliminate Ovarian, Colorectal Cancer in Mice

Rice University bioengineers Amanda Nash (left) and Omid Veiseh with vials of bead-like “drug factories” they created to treat cancer. The beads are designed to continuously produce natural compounds that program the immune system to attack tumors. (Photo by Jeff Fitlow/Rice University)

Immunotherapy treatment could begin human clinical trials this year. Rice University bioengineers have shown they can eradicate advanced-stage ovarian and colorectal cancer in mice in as little as six days with a treatment that could be ready for human clinical trials later this year.

The researchers used implantable “drug factories” the size of a pinhead to deliver continuous, high doses of interleukin2, a natural compound that activates white blood cells to fight cancer...

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Artificial Intelligence to Detect Colorectal Cancer

A Tulane University researcher found that artificial intelligence can accurately detect and diagnose colorectal cancer from tissue scans as well or better than pathologists, according to a new study in the journal Nature Communications.

The study, which was conducted by researchers from Tulane, Central South University in China, the University of Oklahoma Health Sciences Center, Temple University, and Florida State University, was designed to test whether AI could be a tool to help pathologists keep pace with the rising demand for their services.

Pathologists evaluate and label thousands of histopathology images on a regular basis to tell whether someone has cancer...

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Identical Mice, different Gut Bacteria, different Levels of Cancer

Photo of researcher suited up holding tank with mouse inside.
Photo courtesy of ULAM Germ-Free Mouse Facility.

Researchers at the University of Michigan Rogel Cancer Center are shedding new light on the way microorganisms that live in the gastrointestinal tract can affect the development of colorectal cancer.

Some types of gut bacteria are better than others at stimulating certain immune cells, specifically CD8+ T cells, in the body, they found. And while these CD8+ T cells normally help protect the body against cancer, overstimulating them may promote inflammation and exhaust the T cells — which can actually increase susceptibility to cancer, according to new mouse model study published in Cell Reports.

The work will help scientists pinpoint which populations of bacteria are tumor suppressive or tumor promoting and how, says study first au...

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Common Food Additive Found to Affect Gut Microbiota


Impact of the food additive titanium dioxide (E171) on gut microbiota-host interactionFrontiers in Nutrition, 2019

Titanium dioxide nanoparticles E171 may impact human health. University of Sydney research provides new evidence that nanoparticles, which are present in many food items, may have a substantial and harmful influence on human health. E171 is commonly used in high quantities in foods and some medicines as a whitening agent. Found in more than 900 food products such as chewing gum and mayonnaise, E171 is consumed in high proportion everyday by the general population.

Published in Frontiers in Nutrition, the mice study found that consumption of food containing E171 has an impact on the gut microbiota (defined by the trillions of bacteria that inhabit the gut) which coul...

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