colorectal cancers tagged posts

Mouse Study Identifies Bacterial Protein associated with Colorectal Cancers

Newly identified toxin common in E. coli bacteria accelerated colon cancer in study mice; confirming link to human colorectal cancers could pave way for developing preventive drugs. The discovery raises the possibility that some of the roughly two million new cases of colorectal cancer every year around the world originate from brief and seemingly mild food-poisoning events. It also points to the possibility of future drugs that prevent colorectal cancers by neutralizing the newly identified toxin, UshA.

The findings were published January 12 in the January edition of Cancer Discovery.

Prior research has suggested that certain bacteria that reside in the gut can trigger colorectal cancer via persistent infections involving chronic gut inflammation...

Read More

Researchers discover the Microbiome’s role in attacking Cancerous Tumors

The Microbiome's Role in Attacking Cancerous Tumors | Technology ...
Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapyScience, 2020; eabc3421 DOI

Researchers with the Snyder Institute for Chronic Diseases at the Cumming School of Medicine (CSM) have discovered which gut bacteria help our immune system battle cancerous tumours and how they do it. The discovery may provide a new understanding of why immunotherapy, a treatment for cancer that helps amplify the body’s immune response, works in some cases, but not others. The findings, published in Science, show combining immunotherapy with specific microbial therapy boosts the ability of the immune system to recognize and attack cancer cells in some melanoma, bladder and colorectal cancers.

Dr...

Read More