common cold tagged posts

S6K1 and S6K2 are required for Ad-induced activation of IRF3.

Researchers at McMaster University have discovered a critical step in the immune system’s recognition of DNA viruses. It’s a key finding, they say, that could lead to vaccinations for herpes, the common cold or even cancer. A protein, previously known to be involved in metabolism, is critical for the detection of the viruses.

“We have identified an important step in the detection of DNA viruses by the immune system, and have shown that this is absolutely crucial in the response to a vaccine against these infections. If the key immune system component identified in these studies is not triggered, then vaccination fails” said Prof. Lichty.

Wan says this study could have further impact on a number of serious conditions and illnesse...

RSV, labeled with GFP to glow green, infects a sample of lung tissue from a deceased donor. New research shows that the virus produces defective genomes that prompt the immune system to eliminate the pathogen. Credit: University of Pennsylvania

Almost all human beings are exposed to the respiratory syncytial virus, or RSV, before their second birthdays. For most, the symptoms mimic those of the common cold: runny nose, coughing, sneezing, fever. But in some very young infants – and some older adults – the disease can be serious, causing respiratory problems that require hospitalization and increase the risk of developing asthma later in life.

Even in the hospital, doctors can’t do much more than offer supportive care...