common cold virus tagged posts

Common Cold Virus Linked to Potentially Fatal Blood Clotting Disorder

Image: Red-colored region depicts region on platelet factor 4 (PF4) molecule recognized by VITT-like antibodies obtained from patient 2 (adult). Credit: Mercy Daka (co-author) and Dr. Ishac Nazy (co-author)

A new observation suggests that a life-threatening blood clotting disorder can be caused by an infection with adenovirus, one of the most common respiratory viruses in pediatric and adult patients.

Platelets, or thrombocytes, are specialized cellular fragments that form blood clots when we get scrapes and traumatic injuries. Viral infections, autoimmune disease, and other conditions can cause platelet levels to drop throughout the body, termed thrombocytopenia.

After a robust clinical and research collaboration, Stephan Moll, MD, and Jacquelyn Baskin-Miller, MD, both in the UN...

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Molecule that acts on Human Cells might provide hope for ‘Irresistible’ Cold Cure

Small blue blob with yellow innards up against large angular pale green blob with green innards

The molecule (yellow) blocks human NMT (blue), essential for the virus to assemble the capsid ‘shell’ that encloses its RNA genome (green)

Researchers have lab-tested a molecule that can combat the common cold virus by preventing it from hijacking human cells. Early lab-based tests with human cells have shown the molecule’s ability to completely block multiple strains of cold virus, and the team hope to move to animal and then human trials. The results of initial tests are published today in the journal Nature Chemistry.

The common cold is caused by a family of viruses with hundreds of variants, making it nearly impossible to become immune to or vaccinate against all of them. On top of that, the viruses evolve rapidly, meaning they can quickly gain resistance to drugs...

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