Connections Between Metabolism and Immunity tagged posts

Rare Diseases Point to Connections Between Metabolism and Immunity

Jeffrey Rathmell, PhD, left, and Andrew Patterson, PhD, have discovered a new set of metabolic genes that are important for immune cell function. (photo by Susan Urmy)

Overlap in genes suggests a potential new class of inborn errors of immunometabolism. Inherited diseases of metabolism and immunity have more in common than previously recognized, according to a new study published in the journal Science Immunology. The findings point to a new set of metabolic genes that are important for the function of immune system T cells, and they offer insights that could improve care for patients with these disorders.

The study examined genes that cause inborn errors of metabolism (disorders of the processes that cells use to convert food to energy) and inborn errors of immunity (disorders that...

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