COPD tagged posts

Micrograph showing emphysema (left – large empty spaces) and lung tissue with relative preservation of the alveoli (right). Credit: Wikipedia

New research suggests that FPS-ZM1, an antagonist chemical compound that fights RAGE (the receptor for advanced glycation end-products), may treat COPD. In mice it was found this compound reverses the inflammatory response and has a protective role in COPD. “RAGE disturbances in pulmonary disorders are precise and effective strategies with beneficial clinical effects,” said Se-Ran Yang, D.V.M., Ph.D. Kangwon National University, Korea.

In their study, Yang and colleagues investigated the efficacy of RAGE-specific antagonist FPS-ZM1 administration in both in vivo and in vitro COPD models to determine the molecular mechanism by which RAGE influences ...

David Bello, M.D., listens to the heart of a patient at Orlando Health using a new device called HeartBuds, a smartphone and an app. Credit: Orlando Health

“They not only detect sounds inside the body just as well – or better – than traditional stethoscopes, but they are more sanitary,” said David Bello, MD, developer of HeartBuds. “And because they incorporate smartphone technology, we can now record, store and share those sounds as well. This could change the way we approach patient exams in the future.”

The stethoscope was invented in 1816 by French physician René Laennec, and has essentially been unchanged since. But on the eve of its 200th anniversary, the emergence of this new technology could mark the beginning of the end for this medical mainstay.

With HeartBuds, doctors use a sma...