COVID-19 Variants tagged posts

Newly discovered Antibody Protects Against All COVID-19 Variants

Newly discovered antibody protects against all COVID-19 variants
Graphical abstract. Credit: Cell Reports Medicine (2024). DOI: 10.1016/j.xcrm.2024.101668

Researchers have discovered an antibody able to neutralize all known variants of SARS-CoV-2, the virus that causes COVID-19, as well as distantly related SARS-like coronaviruses that infect other animals.

As part of a new study on hybrid immunity to the virus, the large, multi-institution research team led by The University of Texas at Austin discovered and isolated a broadly neutralizing plasma antibody, called SC27, from a single patient...

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Off-Patent Liver Disease Drug could Prevent COVID-19 Infection and Protect against Future Variants, researchers find

Close up of bile duct/liver organoid infected with SARS-CoV-2 – red indicates the virus. (Credit: Teresa Brevini)

Unique experiments involved ‘mini-organs’, animal research, donated human organs, volunteers and patients. Cambridge scientists have identified an off-patent drug that can be repurposed to prevent COVID-19 — and may be capable of protecting against future variants of the virus — in research involving a unique mix of ‘mini-organs’, donor organs, animal studies and patients.

The research, published today in Nature, showed that an existing drug used to treat a type of liver disease is able to ‘lock’ the doorway by which SARS-CoV-2 enters our cells, a receptor on the cell surface known as ACE2...

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Preclinical Demonstration of a Potent, Universal Coronavirus Monoclonal Antibody Therapy for all COVID-19 Variants

Credit: Unsplash/CC0 Public Domain

The SARS-CoV-2 virus that causes COVID-19 has killed 6 million people worldwide since 2019.

Researchers now have discovered a monoclonal antibody that potentially acts as a potent universal coronavirus therapy against the COVID-19 virus and all its variants of concern, including delta and omicron. It also shows effectiveness against the deadly coronaviruses SARS, the Severe Acute Respiratory Syndrome that emerged in China in 2002, and MERS, the Middle East Respiratory Syndrome that appeared in Saudi Arabia in 2012. It even shows effectiveness against several common cold coronaviruses.

This universal activity results from the monoclonal antibody targeting a region of the viral spike protein that is highly conserved among beta-coronaviruses, yet i...

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