
A team of researchers led by Rice University’s Jacob Robinson and the University of Texas Medical Branch’s Peter Kan has developed a technique for diagnosing, managing and treating neurological disorders with minimal surgical risks. The team’s findings were published in Nature Biomedical Engineering.
While traditional approaches for interfacing with the nervous system often require creating a hole in the skull to interface with the brain, the researchers have developed an innovative method known as endocisternal interfaces (ECI), allowing for electrical recording and stimulation o...
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![Synergistic effect between [18F]florbetapir SUVR and CSF p-tau drives [18F]FDG uptake decline in limbic regions. Statistical parametric maps, after correcting for multiple comparisons (false discovery rate corrected at P<0.001), overlaid in a structural MRI scan, reveal areas in which 24-month [18F]FDG uptake decline occurs as a function of the synergistic interaction between baseline [18F]florbetapir SUVR and CSF p-tau measurements. Significant interactive effects were observed in the basal and mesial temporal, orbitofrontal, and anterior and posterior cingulate cortices. The analysis was corrected for age, gender and APOE ε4 status. CSF, cerebrospinal fluid; [18F]FDG, [18F]fluorodeoxyglucose; MRI, magnetic resonance imaging; p-tau, phosphorylated tau; SUVR, standardized uptake value ratio.](https://www.nature.com/mp/journal/vaop/ncurrent/images/mp201637f2.jpg)


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