This image shows DAG (green-labeled peptide) targeting to the brain blood vessel (labeled red) in the hippocampus of the Alzheimer brain. Credit: Ruoslahti Lab, SBP
Peptide recognizes vasculature associated with brain inflammation. Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a peptide that could lead to the early detection of Alzheimer’s disease (AD). The discovery, published in Nature Communications, may also provide a means of homing drugs to diseased areas of the brain to treat AD, Parkinson’s disease, as well as glioblastoma, brain injuries and stroke.
“We have identified a peptide (DAG) that recognizes a protein that is elevated in the brain blood vessels of AD mice and human patients...
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