curcusone D tagged posts

‘Undruggable’ Cancer Protein becomes druggable, thanks to Shrub

jatropha-curcas
Curcusone D, the first synthesized BRAT-1 inhibitor, originally comes from the root of Jatropha curcas, a shrub native to the Americas. (Forest and Kim Starr)

A chemist from Purdue University has found a way to synthesize a compound to fight a previously “undruggable” cancer protein with benefits across a myriad of cancer types.

Inspired by a rare compound found in a shrub native to North America, Mingji Dai, professor of chemistry and a scientist at the Purdue University Center for Cancer Research, studied the compound and discovered a cost-effective and efficient way to synthesize it in the lab...

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