dementia tagged posts

Highly accurate blood test diagnoses Alzheimer’s disease, measures extent of dementia

Kanta Horie
WashU Medicine researcher Kanta Horie, PhD, places a sample in a mass spectrometer that measures protein levels in blood plasma and other fluids. Horie co-led the development of a blood test for Alzheimer’s disease that diagnoses and stages the disease by using mass spectrometry to measure the level of a protein called MTBR-tau243.

Could help determine which patients are likely to benefit from new Alzheimer’s drugs. A newly developed blood test for Alzheimer’s disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a study by researchers at Washington University School of Medicine in St. Louis and Lund University in Sweden.

Several blood tests for Alzheimer’s disease are already clinically available, incl...

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Higher Levels of Leptin indicate Brain Protection against Late-life Dementia

An image of obesity-overweight: A donut with a waist tape
Weight-maintaining hormone key to brain-signal transmission
Contact: Steven Lee, (210) 450-3823, lees22@uthscsa.edu

Weight-maintaining hormone key to brain-signal transmission. A study more closely links obesity to dementia, finding that leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults.

New research is more closely linking obesity to dementia.

Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, according to a study by The University of Texas Health Science Center at San Antonio (UT Health San Antonio).

“The findings support the known role of leptin variations in late-life d...

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AI finds Key Signs that Predict Patient Survival Across Dementia Types

Ai finds key signs that predict patient survival across dementia types
Survival Analysis Based On Dementia Subtypes. Credit: Zhang & Song et al., Communications Medicine

Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients.

The study, published in the February 28 online issue of Communications Medicine, addresses critical challenges in dementia care by pinpointing patients at high risk of near-term death and uncovers the factors that drive this risk.

Unlike previous studies that focused on diagnosing dementia, this research delves into predicting patient prognosis, shedding light on mortality risks and contributing factors in various kinds of dementia.

Dementia has emerged as a major cause of death in societies with increasin...

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Infection with Stomach Bacteria may Increase Risk of Alzheimer’s disease

This shows bacteria and a head.

Researchers from Charité and McGill University quantify association between Helicobacter pylori and Alzheimer’s disease. Infection with the stomach bacterium Helicobacter pylori could increase the risk of developing Alzheimer’s disease: In people over the age of 50, the risk following a symptomatic infection can be an average of 11 percent higher, and even more about ten years after the infection, at 24 percent greater risk. These are the findings of a study by Charité — Universitätsmedizin Berlin and McGill University (Canada), now published in the journal Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.* The researchers analyzed three decades’ worth of patient data.

As today’s populations age, dementia is set to become more common, tripling in prevalence in ...

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