dementia tagged posts

Dr. Andy Shih is Assistant Professor of Neurosciences at the Medical University of South Carolina and senior author on an article published online on Jan. 16, 2017 by the Journal of Cerebral Blood Flow and Metabolism. The article provides preclinical evidence that ministrokes can have a lasting effect on brain function that could contribute to dementia. Credit: Medical University of South Carolina

Evidence overwhelmingly supports a link between cognitive decline and cerebrovascular diseases such as atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy...

Georgios Tsiminis in his photonics laboratory. Credit: University of Adelaide

A 1st step towards a low-cost, portable, broadscale vitamin B12 deficiency test has been developed. Vitamin B12 deficiency is associated with an increased risk of dementia and Alzheimer’s disease. Such a device would enable the tracking of vitamin B12 levels in high-risk patients and early intervention – to top up vitamin B12 levels when low – and help overcome the limitations of current testing methods which are time-consuming and costly.

“Vitamin B12 deficiency has been shown to be a potential modifiable risk factor for dementia and Alzheimer’s disease and is associated with cognitive decline,” says Dr Georgios Tsiminis, Research Fellow at the University of Adelaide...

Researchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer’s disease. Credit: Janickova et al, Bentham Science Publishers

Numerous epidemiological studies have revealed profitable effects of dietary intake of especially fish oil on cognitive decline during aging and dementia. One of the invariable pathologies in AD is degeneration of cholinergic synapses in brain cortex and hippocampus. Current pharmacological interventions are limited to a few drugs that alleviate symptoms but do not slow down the underlying disease processes eg inhibitors of cholinesterases, enzymes that degrade the neurotransmitter acetylcholine, or memantine, a modulator of glutamate neurotransmission.

Within the EU-funded project LipiDiDiet (FP7-211696, the...

UCI professor of neurobiology & behavior Craig Stark, here holding a 3-D-printed model of his own hippocampus, says that “video games may be a nice, viable route” to maintaining cognitive health. Credit: Steve Zylius / UCI

Results suggest novel approaches to maintaining cognition as we age. Along with adding to the trove of research that shows these games can improve eye-hand coordination and reaction time, this finding shows the potential for novel virtual approaches to helping people who lose memory as they age or suffer from dementia.

METHOD: Before and after the 2wk period, the students took memory tests that engaged the brain’s hippocampus, associated with complex learning and memory. They were given a series of pictures of everyday objects to study...