depression tagged posts

Depression linked to presence of immune cells in the brain’s protective layer

Depression linked to presence of immune cells in the brain's protective layer
CSD stress leads to increased numbers of LysM+ myeloid cells in vascular channels connecting skull BM to meninges. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-62840-5

Immune cells released from bone marrow in the skull in response to chronic stress and adversity could play a key role in symptoms of depression and anxiety, say researchers.

The discovery—found in a study in mice—sheds light on the role that inflammation can play in mood disorders and could help in the search for new treatments, in particular for those individuals for whom current treatments are ineffective.

Around 1 billion people will be diagnosed with a mood disorder such as depression or anxiety at some point in their life...

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Traditional Chinese medicinal fungi might show potential for central nervous system diseases

Evaluating traditional Chinese medicinal fungi for bioactive potential
Central nervous system (CNS) diseases and characteristics (AD: Alzheimer’s disease; PD: Parkinson’s disease). Credit: Journal of Food Science (2025). DOI: 10.1111/1750-3841.70230

Shandong researchers suggest that edible and medicinal fungi contain bioactive components with therapeutic potential for central nervous system (CNS) diseases. Findings offer evidence for the potential of these fungi to serve as novel pharmaceuticals or functional foods in the treatment of CNS diseases.

Central nervous system (CNS) diseases involve complex pathophysiology, gradual symptom onset, and significant challenges in therapeutic evaluation...

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The way to Better Mental Health may go through your Stomach

A cup of granola and yogurt on a fragmented background of orange, tan, and blue
Yogurt could help your mood as well as your gut. UVA researchers say a bacterium in fermented foods may help change the way you feel, opening a realm of possible treatments for mental health and other medical issues. (Illustration by Emily Faith Morgan, University Communications)

University of Virginia School of Medicine researchers have discovered how Lactobacillus, a bacterium found in fermented foods and yogurt, helps the body manage stress and may help prevent depression and anxiety.

The findings open the door to new therapies to treat anxiety, depression and other mental health conditions.

UVA researcher Alban Gaultier and collaborators say the discovery is notable because it pinpoints the role of Lactobacillus, separating it out from all the other microorganisms that natura...

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Long COVID can impact Fatigue and Quality of Life worse than some Cancers, finds new study

covid
Credit: Pixabay/CC0 Public Domain

Fatigue is the symptom that most significantly impacts the daily lives of long COVID patients, and can affect quality of life more than some cancers, finds a new study led by researchers at UCL and the University of Exeter.

The research, published in BMJ Open , examines the impact of long COVID on the lives of over 3,750 patients who were referred to a long COVID clinic and used a digital app as part of their NHS treatment for the condition.

Patients were asked to complete questionnaires on the app about how long COVID was affecting them—considering the impact of long COVID on their day-to-day activities, levels of fatigue, depression, anxiety, breathlessness, brain fog, and their quality of life.

The researchers found that many long COVID p...

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