diabetes tagged posts

Self-regulating living implant could end daily insulin injections

Self-regulating living implant could end daily insulin injections
Crystal Capsules. Credit: Technion – Israel Institute of Technology

A pioneering study marks a major step toward eliminating the need for daily insulin injections for people with diabetes. The study was led by Assistant Professor Shady Farah of the Faculty of Chemical Engineering at the Technion—Israel Institute of Technology, in co-correspondence with MIT, and in collaboration with Harvard University, Johns Hopkins University, and the University of Massachusetts. The findings are published in the journal Science Translational Medicine.

The research introduces a living, cell-based implant that can function as an autonomous artificial pancreas, essentially a living drug that is long-term, thanks to a novel crystalline shield-protecting technology...

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A little-known desert berry may hold the key to fighting diabetes

Scientists may have uncovered a surprising new weapon in the fight against diabetes: the fruit of an ancient desert plant. Known as Nitraria roborowskii Kom, this resilient shrub has long been used in traditional medicine but has only recently gained scientific attention. In modern experiments, its fruit extract displayed a remarkable ability to reverse insulin resistance and restore healthy metabolism in diabetic mice.

The results went far beyond stabilizing blood sugar. Researchers found that the extract also corrected lipid imbalances and reduced oxidative stress, two major complications of diabetes. These effects were linked to the activation of a key cellular signaling pathway that helps regulate metabolism...

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Too Much Insulin can be as Dangerous as Too Little

person taking an insulin shot
Millions of Americans use insulin injections to boost levels and treat diabetes, but too much insulin can be deadly too. Researchers have identified a key player in preventing “insulin shock” that might also prove an effective alternative to the hormone. Agamatrix

Researchers describe a key player in the defense mechanism that safeguards against excessive insulin in the body, which can be as harmful as too little. Just over a century has passed since the discovery of insulin, a time period during which the therapeutic powers of the hormone have broadened and refined. Insulin is an essential treatment for type 1 diabetes and often for type 2 diabetes, as well. Roughly 8.4 million Americans use insulin, according to the American Diabetes Association.

One hundred years of research ...

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‘Smart’ Bandages Monitor Wounds and provide Targeted Treatment

A larger version of the smart bandage rests on the back of a gloved hand
A larger version of the smart bandage.

Researchers have developed a flexible electronic bandage for use on chronic wounds, particularly in diabetic patients. The bandage monitors signs of inflammation, collecting medical data, providing medication as needed and stimulate tissue growth.

These kinds of chronic wounds are not just debilitating for the people suffering from them. They are also a drain on healthcare systems, representing a $25 billion financial burden in the United States alone each year.

A new kind of smart bandage developed at Caltech may make treatment of these wounds easier, more effective, and less expensive...

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