diabetes type II tagged posts

Saturated Fat ‘Short-Circuits’ Immune Cells to Trigger Inflammation

A mouse's fat cells are shown surrounded by a network of blood vessels.

A mouse’s fat cells (red) are shown surrounded by a network of blood vessels (green). Source: Daniela Malide, National Heart, Lung, and Blood Institute, National Institutes of Health

UC SF scientists have found a surprising new avenue for potential therapies to reduce risk of type 2 diabetes and other metabolic disorders associated with chronic tissue inflammation in obesity. Inflammation in obesity may be caused, at least in part, by a completely different mechanism from the one that controls normal immune responses. The research shows saturated fats “short-circuit” both mouse and human immune cells, producing an inappropriate inflammatory response as a consequence...

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Intensive Exercise with Intervals ‘more Effective’

Short bursts of Intensive Exercise provide a more “time-efficient” and realistic way of preventing, delaying and managing Type 2 diabetes and also losing weight. Obesity and Type 2 diabetes are linked, with >80% of people with the condition classed as overweight or obese – diet and physical activity interventions are the cornerstones for management of both conditions.

The effects of exercise on Type 2 diabetes and improving the body’s ability to use insulin to absorb blood sugar are well established, but its impact on weight regulation is more controversial...

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How does your microbiome grow?

Bacterial growth rates computed with the new method are shown (top, average; bottom, for specific species, red represents faster replication) for a human subject that underwent a radical dietary change. Compared are days in which only white boiled rice was consumed (grey area) and days of normal diet (white area). A global change in bacterial growth dynamics was observed between dietary regimens. Credit: Weizmann Institute of Science

Bacterial growth rates computed with the new method are shown (top, average; bottom, for specific species, red represents faster replication) for a human subject that underwent a radical dietary change. Compared are days in which only white boiled rice was consumed (grey area) and days of normal diet (white area). A global change in bacterial growth dynamics was observed between dietary regimens. Credit: Weizmann Institute of Science

The reproduction rates of the bacteria in one’s gut may be a good indicator of health or disease, scientists say. In their examination of human microbiome data, the research group found that particular changes in bacterial growth rates are uniquely associated with type II diabetes; others are tied to inflammatory bowel disease, for example.
The study began w...

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