diabetes tagged posts

Scientists from the University of Nottingham have discovered that drinking a cup of coffee can stimulate ‘brown fat’, the body’s own fat-fighting defenses, which could be the key to tackling obesity and diabetes.

The pioneering study, published today in the journal Scientific Reports, is one of the first to be carried out in humans to find components which could have a direct effect on ‘brown fat’ functions, an important part of the human body which plays a key role in how quickly we can burn calories as energy.

Brown adipose tissue (BAT), also known as brown fat, is one of two types of fat found in humans and other mammals...

A new shoe insole technology could help diabetic ulcers heal better while walking.
Credit: Purdue University image/Kayla Wiles

Researchers have developed a shoe insole that could help make the healing process more portable for the 15 percent of Americans who develop ulcers as a result of diabetes.
Diabetes can lead to ulcers that patients don’t even feel or notice until the sight of blood. And because ulcers can’t heal on their own, 14 to 24% of diabetics in the U.S. who experience them end up losing their toes, foot or leg.

Purdue University researchers have developed a shoe insole that could help make the healing process more portable for the 15 percent of Americans who develop ulcers as a result of diabetes...

Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance

A new study by Australian researchers, out today, is challenging what we know about the causes of diabetes. The new research points to fat tissue as a source of disease, and widens our understanding beyond the traditional focus on liver and pancreas as the main culprits. The findings, uncovered in mice, are published in the high-impact journal Cell Metabolism.

The new research is centred around the surprising finding that protein kinase C epsilon (PKCε), known to be involved in diabetes, isn’t acting in the liver or the pancreas as was once assumed. Researchers have long known that PKCε is important for the development of diabetes...

The image represents the first proof of principle for the successful regeneration of a functional organ (the skin) inside a mammal, by a technique known as AAV-based in vivo reprogramming. Epithelial (skin) tissues were generated by converting one cell type (red: mesenchymal cells) to another (green: basal keratinocytes) within a large ulcer in a laboratory mouse model.
Credit: Salk Institute

Plastic surgery to treat large cutaneous ulcers, including those seen in people with severe burns, bedsores or chronic diseases such as diabetes, may someday be a thing of the past. Scientists at the Salk Institute have developed a technique to directly convert the cells in an open wound into new skin cells...