Diabetic Wounds tagged posts

Researchers at Indiana University School of Medicine are looking for ways to heal wounds by using a healing protein that is active in fetuses, but largely inactive in adults and absent in diabetic adults.

“We already know from previous studies at other institutions that if a fetus is wounded, it can regenerate the tissue, or repair it to be like new,” said Chandan K. Sen, PhD, associate vice president of military and applied research, the J. Stanley Battersby chair and distinguished professor of surgery and director of the Indiana Center for Regenerative Medicine and Engineering at Indiana University School of Medicine. “But after birth, such regenerative wound healing ability is lost. Healing in adults is relatively inefficient often associated with undesirable scar formation.”

Sustained release of stromal cell derived factor-1 from an antioxidant thermoresponsive hydrogel enhances dermal wound healing in diabetes

Antioxidant bandage delivers healing protein. At some point in their lives, 15% of people with diabetes will develop a painful and hard-to-treat foot ulcer. 24% percent of those affected will require a lower-leg amputation because of it. And, in some instances, what seems like a harmless sore might even lead to death. A Northwestern University team has developed a new treatment. Called a “regenerative bandage,” the novel material heals diabetic wounds 4X faster than a standard bandage and has the added benefit of promoting healing without side effects.

“Foot ulcers cause many serious problems for diabetic patients,” said Prof. Guillermo Ameer...