dietary fiber tagged posts

Dietary Fiber found to Regulate Gut Bacteria’s use of Tryptophan, Impacting Health

Dietary fibers make our gut bacteria behave healthy
The essential amino acid tryptophan is converted in the large intestine into either beneficial or harmful substances. The research shows that tryptophan contributes to the production of the healthy substances Indole lactic acid (ILA) and Indole propionic acid (IPA) when we consume sufficient amounts of dietary fiber. However, if we do not get enough dietary fiber, tryptophan will be converted into the substance indole, which is associated with adverse health effects. The figure is created with BioRender (biorender.com) by Martin Frederik Laursen. Credit: The figure is created with BioRender (biorender.com) by Martin Frederik Laursen.

We get healthy dietary fiber from consuming fruits, vegetables, and whole grains...

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Dietary Fiber in the Gut may Help with Skin Allergies

A Monash University study exploring the emerging gut-skin axis has found that microbial fermentation of dietary fibre in the gut can protect against allergic skin disease. The research could potentially lead to novel treatments to prevent or treat allergies.

Professor Ben Marsland from the Central Clinical School’s Department of Immunology, together with Swiss colleagues at the University Hospital of Lausanne (CHUV), showed that the fermentation of fibre in the gut by bacteria and subsequent production of short-chain fatty acids (SCFAs), in particular butyrate, protected against atopic dermatitis in mice.

The research was published today in Mucosal Immunology.

While it is well established that the gut microbiome shapes the immune system, the influence it has on the skin is le...

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Dietary Fiber improves outcomes for Melanoma Patients on Immunotherapy

Examples of dietary fiber, photo provided by NIH

Melanoma patients receiving therapy that makes it easier for their immune system to kill cancer cells respond to treatment better when their diet is rich in fiber, according to a large, international research collaboration that includes the Oregon State University College of Pharmacy.

Published today in Science, the study led by the University of Texas and the National Institutes of Health is a promising development in the fight against multiple types of cancer including melanoma, the most deadly form of skin cancer, the researchers said.

Nationwide, melanoma is the fifth-most common cancer...

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Dietary Fiber Reduces Brain Inflammation during Aging

Butyrate and Dietary Soluble Fiber Improve Neuroinflammation Associated With Aging in Mice. Frontiers in Immunology, 2018; 9 DOI: 10.3389/fimmu.2018.01832

Butyrate and Dietary Soluble Fiber Improve Neuroinflammation Associated With Aging in Mice. Frontiers in Immunology, 2018; 9 DOI: 10.3389/fimmu.2018.01832

As mammals age, immune cells in the brain known as microglia become chronically inflamed. In this state, they produce chemicals known to impair cognitive and motor function. That’s one explanation for why memory fades and other brain functions decline during old age. But, according to a new study from the University of Illinois, there may be a remedy to delay the inevitable: dietary fiber.

Dietary fiber promotes the growth of good bacteria in the gut. When these bacteria digest fiber, they produce short-chain-fatty-acids (SCFAs), including butyrate, as byproducts...

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