downstream core promoter region (DPR) tagged posts

Artificial Intelligence Aids Gene Activation Discovery

With the aid of artificial intelligence, UC San Diego scientists have solved a long-standing puzzle in human gene activation. The discovery described in the journal Nature could be used to control gene activation in biotechnology and biomedical applications.

Machine learning enables long-awaited code breakthrough with potential applications in biomedicine. Scientists have long known that human genes spring into action through instructions delivered by the precise order of our DNA, directed by the four different types of individual links, or “bases,” coded A, C, G and T.

Nearly 25% of our genes are widely known to be transcribed by sequences that resemble TATAAA, which is called the “TATA box...

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