drug delivery tagged posts

Treatment reverses paralysis in mice; offers a general delivery platform for neurologic drugs. Currently there’s no treatment for botulism once the toxin gets into neurons...

A novel tiny, soft robot with soft caterpillar-like legs which is adaptable to adverse environment and can carry heavy load was developed. Credit: City University of Hong Kong

A novel tiny, soft robot with caterpillar-like legs capable of carrying heavy loads and adaptable to adverse environment was developed from a research led by City University of Hong Kong (CityU). This mini delivery-robot could pave way for medical technology advancement such as drugs delivery in human body.

Around the world, there has been research about developing soft milli-robots. But the CityU’s new design with multi-legs helps reduce friction significantly, so that the robot can move efficiently inside surfaces within the body lined with, or entirely immersed in, body fluids such as blood or mucus.

What makes th...

Tests showed that subcutaneous implants, left, of a hydrogel developed at Rice University encouraged blood vessel and cell growth as new tissue replaced the degrading gel. Credit: Hartgerink Research Group/Rice University

A synthetic, injectable hydrogel developed to deliver drugs and encourage tissue growth turns out to have therapeutic properties all its own. Researchers in the Rice lab of chemist and bioengineer Jeffrey Hartgerink had just such an experience with the hydrogels they developed as a synthetic scaffold to deliver drugs and encourage the growth of cells and blood vessels for new tissue.

To do so, they often tested the gels by infusing them before injection with bioactive small molecules, cells or proteins...

3-D-printed microfish contain functional nanoparticles that enable them to be self-propelled, chemically powered and magnetically steered. The microfish are also capable of removing and sensing toxins. Credit: J. Warner, UC San Diego Jacobs School of Engineering.

These microrobots are powered by H2O2 and magnetically controlled. They will inspire a new generation of ‘smart’ microrobots that have diverse capabilities such as detoxification, sensing and directed drug delivery, the nanoengineers of University of California, SD said.

The technique used to fabricate the microfish provides many improvements over other methods with locomotion mechanisms, eg microjet engines, microdrillers and microrockets...